STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNK2Activated CDC42 kinase 1. (843 aa)    
Predicted Functional Partners:
CDC42
Cell division control protein 42 homolog isoform X1.
    
 
 0.954
GRB2
Growth factor receptor-binding protein 2.
    
 0.830
SH3RF3
E3 ubiquitin-protein ligase SH3RF3.
    
 
 0.709
NCK2
Cytoplasmic protein NCK2.
    
 
 0.663
GRAP2
GRB2 related adaptor protein 2.
    
 0.540
GRAP
GRB2-related adapter protein isoform X1.
    
 0.540
ARHGAP31
Rho GTPase activating protein 31.
      
 0.537
CLTC
Clathrin heavy chain 1 isoform X1.
    
 
 0.499
CLTCL1
Clathrin heavy chain 2 isoform X1.
    
 
 0.499
WASL
Neural Wiskott-Aldrich syndrome protein isoform X1.
    
 
 0.486
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.