STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAPGEF1Rap guanine nucleotide exchange factor 1 isoform X1. (1225 aa)    
Predicted Functional Partners:
CRKL
Proto-oncogene C-crk.
    
 0.996
CRK
Adapter molecule crk.
    
 0.994
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.974
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.974
RAP1A
Ras-related protein Rap-1A.
    
 0.970
RAP1B
Ras-related protein Rap-1B.
    
 0.970
RHOQ
Rho-related GTP-binding protein RhoQ isoform X1.
    
 0.950
GRB2
Growth factor receptor-binding protein 2.
   
 0.864
NEDD9
Enhancer of filamentation 1.
    
 0.734
BCAR1
Breast cancer anti-estrogen resistance protein 1.
    
 0.730
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.