STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APLFAprataxin and PNK-like factor. (381 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5.
    
 
 0.947
XRCC6
X-ray repair cross-complementing protein 6.
    
 
 0.911
ENSACUP00000006297
annotation not available
    
 
 0.872
LIG3
DNA ligase 3 isoform X1.
    
 
 0.747
LIG4
DNA ligase 4.
    
 
 0.722
TDP1
Tyrosyl-DNA phosphodiesterase 1.
    
 
 0.705
PARP1
Poly [ADP-ribose] polymerase 1.
    
 
 0.702
PARP3
Poly [ADP-ribose] polymerase 3 isoform X1.
    
 
 0.675
WRN
WRN RecQ like helicase.
      
 0.668
APTX
Aprataxin isoform X1.
      
 0.659
Your Current Organism:
Athene cunicularia
NCBI taxonomy Id: 194338
Other names: A. cunicularia, Speotyto cunicularia, burrowing owl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.