STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobAuroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:12949; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family. (267 aa)    
Predicted Functional Partners:
CT2239
Porphyrin biosynthesis protein, putative; Similar to N-terminal 140 aa of E. coli cysG (siroheme synthase) and adjacent to hemD, which is similar to the remainder of cysG; identified by similarity to EGAD:6104; match to protein family HMM TIGR01470.
 
 0.997
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.992
cbiL
Precorrin-2 C20-methyltransferase; Identified by similarity to EGAD:18341; match to protein family HMM PF00590; Belongs to the precorrin methyltransferase family.
 
 
 0.984
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 0.964
CT2238
Siroheme synthetase, putative; Identified by similarity to EGAD:14346; match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.
 
 
0.925
CT1763
uroporphyrin-III C-methyltransferase; Identified by similarity to EGAD:6870; match to protein family HMM PF00590.
  
  
 
0.921
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.911
cbiCH
precorrin-3B C17-methyltransferase/precorrin-8X methylmutase; Identified by similarity to EGAD:15379; similarity to EGAD:17916; match to protein family HMM PF00590; match to protein family HMM PF02570; match to protein family HMM TIGR01466.
  
 0.903
CT0937
Identified by match to protein family HMM PF00881; match to protein family HMM TIGR02476.
 
  
 0.897
cbiET
Precorrin-6y c5,15-methyltransferase, decarboxylating; Identified by similarity to EGAD:12801; match to protein family HMM PF00590; match to protein family HMM TIGR02467; match to protein family HMM TIGR02469.
 
  
 0.876
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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