STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CT10485-formyltetrahydrofolate cyclo-ligase, putative; Identified by match to protein family HMM PF01812; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa)    
Predicted Functional Partners:
mtd
Methylenetetrahydrofolate dehydrogenase; Identified by similarity to EGAD:54210; match to protein family HMM PF00763; match to protein family HMM PF02882.
    
 0.937
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.936
CT0720
Serine cycle enzyme, putative; Identified by similarity to EGAD:33559; match to protein family HMM PF04961.
    
 0.924
purT
Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family.
    
 0.904
rpiB
Ribose-5-phosphate isomerase; Identified by similarity to EGAD:16338; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120.
       0.789
ppk-2
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP); Belongs to the polyphosphate kinase 1 (PPK1) family.
       0.779
CT1051
Hypothetical protein; Identified by Glimmer2; putative.
       0.774
CT1052
Peptidase, M20/M25/M40 family; Identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01891.
  
    0.697
CT2221
Membrane protein, putative; Identified by similarity to EGAD:164635; match to protein family HMM PF01694.
  
    0.588
CT1047
Hypothetical protein; Identified by Glimmer2; putative.
       0.572
Your Current Organism:
Chlorobaculum tepidum
NCBI taxonomy Id: 194439
Other names: C. tepidum TLS, Chlorobaculum tepidum TLS, Chlorobium tepidum TLS
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.