node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OOG67577.1 | OOG67605.1 | B0E45_23315 | B0E45_23465 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
OOG67577.1 | OOG68338.1 | B0E45_23315 | B0E45_18670 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AdoMet synthase family. | 0.776 |
OOG67577.1 | OOG70022.1 | B0E45_23315 | B0E45_14560 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.801 |
OOG67577.1 | OOG74003.1 | B0E45_23315 | B0E45_06930 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.909 |
OOG67577.1 | folD | B0E45_23315 | B0E45_25640 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.731 |
OOG67577.1 | gcvP | B0E45_23315 | B0E45_21845 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.788 |
OOG67577.1 | glyA | B0E45_23315 | B0E45_03290 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.679 |
OOG67577.1 | metAA | B0E45_23315 | B0E45_09780 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.454 |
OOG67577.1 | metE | B0E45_23315 | B0E45_11770 | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.859 |
OOG67605.1 | OOG67577.1 | B0E45_23465 | B0E45_23315 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
OOG67605.1 | OOG68338.1 | B0E45_23465 | B0E45_18670 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AdoMet synthase family. | 0.749 |
OOG67605.1 | OOG70022.1 | B0E45_23465 | B0E45_14560 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.813 |
OOG67605.1 | OOG74003.1 | B0E45_23465 | B0E45_06930 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylenetetrahydrofolate reductase [NAD(P)H]; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.927 |
OOG67605.1 | folD | B0E45_23465 | B0E45_25640 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.749 |
OOG67605.1 | gcvP | B0E45_23465 | B0E45_21845 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.807 |
OOG67605.1 | glyA | B0E45_23465 | B0E45_03290 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.679 |
OOG67605.1 | metAA | B0E45_23465 | B0E45_09780 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.641 |
OOG67605.1 | metE | B0E45_23465 | B0E45_11770 | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.699 |
OOG68338.1 | OOG67577.1 | B0E45_18670 | B0E45_23315 | Methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AdoMet synthase family. | Catalyzes the formation of methionine from L-homocysteine and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.776 |
OOG68338.1 | OOG67605.1 | B0E45_18670 | B0E45_23465 | Methionine adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AdoMet synthase family. | Methyltetrahydrofolate--corrinoid methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.749 |