| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APG89897.1 | APG90060.1 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0736 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Dioxygenase reductase subunit; Region:COG1018C. | 0.916 |
| APG89897.1 | APG90682.1 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1373 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Metallophosphoesterase YhaO; Region:COG0420L. | 0.677 |
| APG89897.1 | APG92946.1 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch3697 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Phosphatidic acid phosphatase type 2; Region:COG0671I. | 0.564 |
| APG89897.1 | cya-19 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2817 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Adenylate cyclase; Region:COG0633C. | 0.937 |
| APG89897.1 | cypE | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0060 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Bifunctional reductase 2; Region:COG2124QV; Belongs to the cytochrome P450 family. | 0.961 |
| APG89897.1 | fadD | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0488 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | long-chain-fatty-acid--CoA ligase FadD; Region:COG0318IQ. | 0.961 |
| APG89897.1 | hcr | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0914 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | NADH oxidoreductase Hcr; Region:COG1018C. | 0.916 |
| APG89897.1 | paaE | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2915 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Phenylacetic acid degradation NADH oxidoreductase PaaE; Region:COG1018C. | 0.916 |
| APG89897.1 | polA | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0165 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.749 |
| APG90060.1 | APG89897.1 | SAMCFNEI73_Ch0736 | SAMCFNEI73_Ch0569 | Dioxygenase reductase subunit; Region:COG1018C. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.916 |
| APG90060.1 | cypE | SAMCFNEI73_Ch0736 | SAMCFNEI73_Ch0060 | Dioxygenase reductase subunit; Region:COG1018C. | Bifunctional reductase 2; Region:COG2124QV; Belongs to the cytochrome P450 family. | 0.747 |
| APG90682.1 | APG89897.1 | SAMCFNEI73_Ch1373 | SAMCFNEI73_Ch0569 | Metallophosphoesterase YhaO; Region:COG0420L. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.677 |
| APG90682.1 | cypE | SAMCFNEI73_Ch1373 | SAMCFNEI73_Ch0060 | Metallophosphoesterase YhaO; Region:COG0420L. | Bifunctional reductase 2; Region:COG2124QV; Belongs to the cytochrome P450 family. | 0.702 |
| APG90682.1 | polA | SAMCFNEI73_Ch1373 | SAMCFNEI73_Ch0165 | Metallophosphoesterase YhaO; Region:COG0420L. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
| APG92946.1 | APG89897.1 | SAMCFNEI73_Ch3697 | SAMCFNEI73_Ch0569 | Phosphatidic acid phosphatase type 2; Region:COG0671I. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.564 |
| APG92946.1 | cypE | SAMCFNEI73_Ch3697 | SAMCFNEI73_Ch0060 | Phosphatidic acid phosphatase type 2; Region:COG0671I. | Bifunctional reductase 2; Region:COG2124QV; Belongs to the cytochrome P450 family. | 0.769 |
| APG92946.1 | fadD | SAMCFNEI73_Ch3697 | SAMCFNEI73_Ch0488 | Phosphatidic acid phosphatase type 2; Region:COG0671I. | long-chain-fatty-acid--CoA ligase FadD; Region:COG0318IQ. | 0.756 |
| APG92946.1 | rplF | SAMCFNEI73_Ch3697 | SAMCFNEI73_Ch1493 | Phosphatidic acid phosphatase type 2; Region:COG0671I. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.795 |
| cya-19 | APG89897.1 | SAMCFNEI73_Ch2817 | SAMCFNEI73_Ch0569 | Adenylate cyclase; Region:COG0633C. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.937 |
| cya-19 | cypE | SAMCFNEI73_Ch2817 | SAMCFNEI73_Ch0060 | Adenylate cyclase; Region:COG0633C. | Bifunctional reductase 2; Region:COG2124QV; Belongs to the cytochrome P450 family. | 0.714 |