Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpaEPilus assembly protein CpaE; Region:COG4963UW. (427 aa)    
Predicted Functional Partners:
tadB
Type II/IV secretion system protein TadB, Flp pilus assembly protein TadB; Region:COG4965UW.
 
  
 0.959
cpaB
Pilus assembly protein CpaB; Region:COG3745UW.
 
  
 0.957
cpaC
Pilus assembly protein CpaC, contains signal peptide; Region:COG4964UW; Belongs to the bacterial secretin family.
 
  
 0.955
tadC
Components of type IV pilus TadC; Region:COG2064W.
 
  
 0.941
cpaF
Pilus assembly protein ATPase CpaF; Region:COG4962UW.
 
  
 0.930
cpaD
Pilus assembly protein CpaD; Region:COG5461W.
 
     0.923
tadG
Flp pilus assembly protein TadG; Region:COG4961UW.
 
    0.920
cpaB-3
Flp pilus assembly protein CpaB; Region:COG3745UW.
 
  
 0.920
tadB-3
Pilus assembly protein TadB; Region:COG4965UW.
 
  
 0.920
APG89461.1
Flp pilus assembly protein, pilin Flp; Region:COG3847UW.
 
  
 0.909
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
Server load: low (22%) [HD]