Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pitLow-affinity inorganic phosphate transporter Pit; Region:COG0306P. (334 aa)    
Predicted Functional Partners:
APG89488.1
Pit accessory protein; Region:COG1392S.
 
  
 0.990
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.602
APG89827.1
UDP-galactose-lipid carrier transferase; Region:COG2326C.
  
  
 0.512
gltB-2
Ferredoxin-dependent glutamate synthase 1; Region:COG0067E.
  
  
 0.502
recF
DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
       0.486
pyrH
Uridylate kinase PyrH; Catalyzes the reversible phosphorylation of UMP to UDP.
   
    0.463
APG89490.1
Hypothetical protein; Region:COG5588S.
       0.456
APG89491.1
Hypothetical protein; Region:COG5486S.
       0.456
APG91031.1
Na+/Pi-cotransporter; Region:COG1283P.
     
 0.451
lysS
lysine--tRNA ligase LysS; Region:COG1190J; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
    0.421
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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