Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ttgAToluene efflux pump periplasmic linker protein TtgA; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (401 aa)    
Predicted Functional Partners:
acrF
Acriflavine resistance protein F; Region:COG0841V.
 0.993
tolC
TolC outer membrane protein; Region:COG1538M.
 
 0.973
bepG
Efflux pump membrane transporter BepG; Region:COG0841V.
 0.969
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.921
APG91705.1
Transporter; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.909
nolG
Nodulation protein NolG; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.896
bepE
Efflux pump membrane transporter BepE; Region:COG0841V.
 
 0.855
bepG-2
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 0.852
bepR
HTH-type transcriptional repressor BepR; Region:COG1309K.
       0.635
emrK
Multidrug resistance protein K; Region:COG1566V.
 
   
 0.607
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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