| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APG89651.1 | gst-2 | SAMCFNEI73_Ch0319 | SAMCFNEI73_Ch0321 | NAD-dependent epimerase/dehydratase; Region:COG0451M. | Glutathione S-transferase family protein; Region:COG0625O. | 0.866 |
| APG89651.1 | queG | SAMCFNEI73_Ch0319 | SAMCFNEI73_Ch0320 | NAD-dependent epimerase/dehydratase; Region:COG0451M. | Electron transport protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.840 |
| APG89651.1 | uppP | SAMCFNEI73_Ch0319 | SAMCFNEI73_Ch0322 | NAD-dependent epimerase/dehydratase; Region:COG0451M. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.595 |
| gst-2 | APG89651.1 | SAMCFNEI73_Ch0321 | SAMCFNEI73_Ch0319 | Glutathione S-transferase family protein; Region:COG0625O. | NAD-dependent epimerase/dehydratase; Region:COG0451M. | 0.866 |
| gst-2 | queG | SAMCFNEI73_Ch0321 | SAMCFNEI73_Ch0320 | Glutathione S-transferase family protein; Region:COG0625O. | Electron transport protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.840 |
| gst-2 | uppP | SAMCFNEI73_Ch0321 | SAMCFNEI73_Ch0322 | Glutathione S-transferase family protein; Region:COG0625O. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.600 |
| macB | rsmA | SAMCFNEI73_Ch2354 | SAMCFNEI73_Ch1210 | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.645 |
| macB | uppP | SAMCFNEI73_Ch2354 | SAMCFNEI73_Ch0322 | Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.511 |
| mprF | murG | SAMCFNEI73_Ch1241 | SAMCFNEI73_Ch2462 | Phosphatidylglycerol lysyltransferase MprF; Region:COG0392S. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.486 |
| mprF | uppP | SAMCFNEI73_Ch1241 | SAMCFNEI73_Ch0322 | Phosphatidylglycerol lysyltransferase MprF; Region:COG0392S. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.475 |
| mraY | murG | SAMCFNEI73_Ch2465 | SAMCFNEI73_Ch2462 | phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.998 |
| mraY | uppP | SAMCFNEI73_Ch2465 | SAMCFNEI73_Ch0322 | phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.928 |
| mraY | uppS | SAMCFNEI73_Ch2465 | SAMCFNEI73_Ch1630 | phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Undecaprenyl pyrophosphate synthase UppS; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.578 |
| murG | mprF | SAMCFNEI73_Ch2462 | SAMCFNEI73_Ch1241 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Phosphatidylglycerol lysyltransferase MprF; Region:COG0392S. | 0.486 |
| murG | mraY | SAMCFNEI73_Ch2462 | SAMCFNEI73_Ch2465 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | phospho-N-acetylmuramoyl-pentapeptide- transferase MraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.998 |
| murG | uppP | SAMCFNEI73_Ch2462 | SAMCFNEI73_Ch0322 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.416 |
| murG | uppS | SAMCFNEI73_Ch2462 | SAMCFNEI73_Ch1630 | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Undecaprenyl pyrophosphate synthase UppS; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.477 |
| queA | queG | SAMCFNEI73_Ch1973 | SAMCFNEI73_Ch0320 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Electron transport protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.828 |
| queA | uppP | SAMCFNEI73_Ch1973 | SAMCFNEI73_Ch0322 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Undecaprenyl-diphosphatase UppP; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.466 |
| queG | APG89651.1 | SAMCFNEI73_Ch0320 | SAMCFNEI73_Ch0319 | Electron transport protein YjeS; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | NAD-dependent epimerase/dehydratase; Region:COG0451M. | 0.840 |