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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
frkFructokinase Frk; Region:COG0524G. (308 aa)    
Predicted Functional Partners:
mtlK
Mannitol 2-dehydrogenase MtlK; Region:COG0246G; Belongs to the mannitol dehydrogenase family.
 
  
 0.957
aglA
Alpha-glucosidase AglA; Region:COG0366G.
 
  
 0.949
aglA-2
Alpha-glucosidase AglA; Region:COG0366G.
 
  
 0.949
pgi
Glucose-6-phosphate isomerase; Region:COG0166G; Belongs to the GPI family.
  
 
 0.928
xylA
Xylose isomerase XylA; Region:COG2115G; Belongs to the xylose isomerase family.
 
  
 0.928
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase Pfp; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.921
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Region:COG2222M.
  
 
 0.916
glmS-2
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.914
pmi
Mannose-6-phosphate isomerase Pmi; Region:COG2942G.
    
 0.908
mak
Fructokinase Mak; Region:COG1940KG.
  
 
 0.906
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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