STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceAIsocitrate lyase AceA; Region:COG2224C. (429 aa)    
Predicted Functional Partners:
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
 
 
 0.996
acnA
Aconitate hydratase AcnA; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
 
 0.931
glcF
Glycolate oxidase iron-sulfur subunit GlcF; Region:COG0247C.
     
 0.915
gyaR
Glyoxylate reductase GyaR; Region:COG1052CHR; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.912
ghrA
Glyoxylate/hydroxypyruvate reductase A; Region:COG0111HR.
   
 
 0.912
eda
2-dehydro-3-deoxy-phosphogluconate aldolase Eda; Region:COG0800G.
     
 0.906
glcD
Glycolate oxidase subunit GlcD; Region:COG0277C.
     
 0.904
glcE
Glycolate oxidase subunit GlcE; Region:COG0277C.
     
 0.904
ackA
Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
  
 0.846
allA
Ureidoglycolate hydrolase; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
     
 0.808
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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