STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
adhAAlcohol dehydrogenase AdhA; Region:COG1064G. (341 aa)    
Predicted Functional Partners:
acoD
Acetaldehyde dehydrogenase 2; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
 
 
 0.905
ald-3
Aldehyde dehydrogenase; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
 
 
 0.905
gabD-2
Succinate-semialdehyde dehydrogenase [NADP+]; Region:COG1012C.
 
 
 0.905
APG90122.1
Dienelactone hydrolase family protein; Region:COG0412Q.
  
    0.697
mdh
NAD-dependent methanol dehydrogenase Mdh; Region:COG1454C.
  
 
 0.625
APG90120.1
Hypothetical protein; Region:COG5331S.
       0.445
APG89897.1
Erythronolide synthase, modules 3 and 4; Region:COG0236IQ.
  
 
0.430
guaB
Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.412
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.