Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vraBacetyl-CoA C-acetyltransferase VraB; Region:COG0183I; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)    
Predicted Functional Partners:
APG92181.1
enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase; Region:COG1024I.
 0.999
fadB-2
3-hydroxyacyl-CoA dehydrogenase; Region:COG1024I.
  
 0.998
hbdA
3-hydroxybutyryl-CoA dehydrogenase; Region:COG1250I.
 0.990
APG91799.1
acyl-CoA dehydrogenase YngJ; Region:COG1960I.
 
 0.967
gltA
Citrate synthase GltA; Region:COG0372C; Belongs to the citrate synthase family.
  
 0.947
APG90495.1
AIPM/hcit synthase family transferase; Region:COG0119E; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.926
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 
 0.926
APG92928.1
Coenzyme A transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
 
  
 0.923
acsA
Acetoacetyl-coenzyme A synthetase AcsA; Region:COG0365I.
  
 
 0.920
APG92268.1
acetyl-CoA synthetase; Region:COG0365I.
  
 
 0.920
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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