| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APG90285.1 | ispH | SAMCFNEI73_Ch0964 | SAMCFNEI73_Ch0965 | Hypothetical protein; Region:COG3759S. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.840 |
| APG90285.1 | rnhA | SAMCFNEI73_Ch0964 | SAMCFNEI73_Ch0967 | Hypothetical protein; Region:COG3759S. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.619 |
| APG90285.1 | thrB | SAMCFNEI73_Ch0964 | SAMCFNEI73_Ch0966 | Hypothetical protein; Region:COG3759S. | Homoserine kinase ThrB; Region:COG2334T; Belongs to the pseudomonas-type ThrB family. | 0.657 |
| dnaQ | polA | SAMCFNEI73_Ch0005 | SAMCFNEI73_Ch0165 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.651 |
| dnaQ | rnhA | SAMCFNEI73_Ch0005 | SAMCFNEI73_Ch0967 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.913 |
| dnaQ | topA | SAMCFNEI73_Ch0005 | SAMCFNEI73_Ch1418 | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.478 |
| flgC | rnhA | SAMCFNEI73_Ch0665 | SAMCFNEI73_Ch0967 | Flagellar basal-body rod protein FlgC; Region:COG1558N; Belongs to the flagella basal body rod proteins family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.533 |
| ispH | APG90285.1 | SAMCFNEI73_Ch0965 | SAMCFNEI73_Ch0964 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Hypothetical protein; Region:COG3759S. | 0.840 |
| ispH | polA | SAMCFNEI73_Ch0965 | SAMCFNEI73_Ch0165 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.459 |
| ispH | rnhA | SAMCFNEI73_Ch0965 | SAMCFNEI73_Ch0967 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.711 |
| ispH | thrB | SAMCFNEI73_Ch0965 | SAMCFNEI73_Ch0966 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | Homoserine kinase ThrB; Region:COG2334T; Belongs to the pseudomonas-type ThrB family. | 0.711 |
| polA | dnaQ | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch0005 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.651 |
| polA | ispH | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch0965 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.459 |
| polA | rnhA | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch0967 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.682 |
| polA | rnhB | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch0875 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.925 |
| polA | ssb | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch1947 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.887 |
| polA | thrB | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch0966 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Homoserine kinase ThrB; Region:COG2334T; Belongs to the pseudomonas-type ThrB family. | 0.479 |
| polA | topA | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch1418 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.838 |
| polA | valS | SAMCFNEI73_Ch0165 | SAMCFNEI73_Ch1648 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | valine--tRNA ligase ValS; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.567 |
| rnhA | APG90285.1 | SAMCFNEI73_Ch0967 | SAMCFNEI73_Ch0964 | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Hypothetical protein; Region:COG3759S. | 0.619 |