| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APG89897.1 | betA | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1007 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.474 |
| APG89897.1 | betB | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1009 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.563 |
| APG89897.1 | betC | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1010 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Choline-sulfatase BetC; Region:COG3119P. | 0.816 |
| APG89897.1 | betI | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1011 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.422 |
| APG89897.1 | rutR | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2818 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | HTH-type transcriptional regulator RutR; Region:COG1309K. | 0.422 |
| APG89897.1 | stcD-2 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0749 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | N-methylproline demethylase StcD; Region:COG0446I. | 0.576 |
| APG90330.1 | APG90331.1 | SAMCFNEI73_Ch1012 | SAMCFNEI73_Ch1013 | Transmembrane protein; Region:COG3247S. | GGDEF/EAL sensory box protein; Region:COG0517T. | 0.489 |
| APG90330.1 | betI | SAMCFNEI73_Ch1012 | SAMCFNEI73_Ch1011 | Transmembrane protein; Region:COG3247S. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.495 |
| APG90331.1 | APG90330.1 | SAMCFNEI73_Ch1013 | SAMCFNEI73_Ch1012 | GGDEF/EAL sensory box protein; Region:COG0517T. | Transmembrane protein; Region:COG3247S. | 0.489 |
| APG90331.1 | betI | SAMCFNEI73_Ch1013 | SAMCFNEI73_Ch1011 | GGDEF/EAL sensory box protein; Region:COG0517T. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.401 |
| APG91974.1 | betA | SAMCFNEI73_Ch2698 | SAMCFNEI73_Ch1007 | Proline/glycine betaine ABC transporter, substrate-binding protein; Region:COG2113E. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.450 |
| APG91974.1 | betI | SAMCFNEI73_Ch2698 | SAMCFNEI73_Ch1011 | Proline/glycine betaine ABC transporter, substrate-binding protein; Region:COG2113E. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.708 |
| betA | APG89897.1 | SAMCFNEI73_Ch1007 | SAMCFNEI73_Ch0569 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.474 |
| betA | APG91974.1 | SAMCFNEI73_Ch1007 | SAMCFNEI73_Ch2698 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Proline/glycine betaine ABC transporter, substrate-binding protein; Region:COG2113E. | 0.450 |
| betA | betB | SAMCFNEI73_Ch1007 | SAMCFNEI73_Ch1009 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | 0.928 |
| betA | betI | SAMCFNEI73_Ch1007 | SAMCFNEI73_Ch1011 | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.508 |
| betB | APG89897.1 | SAMCFNEI73_Ch1009 | SAMCFNEI73_Ch0569 | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.563 |
| betB | betA | SAMCFNEI73_Ch1009 | SAMCFNEI73_Ch1007 | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline dehydrogenase BetA; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. | 0.928 |
| betB | betC | SAMCFNEI73_Ch1009 | SAMCFNEI73_Ch1010 | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | Choline-sulfatase BetC; Region:COG3119P. | 0.804 |
| betB | betI | SAMCFNEI73_Ch1009 | SAMCFNEI73_Ch1011 | Betaine aldehyde dehydrogenase BetB; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid. | HTH-type transcriptional regulator BetI; Repressor involved in choline regulation of the bet genes. | 0.841 |