| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fhs | purC | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch1999 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | 0.867 |
| fhs | purD | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch0899 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylamine--glycine ligase PurD; Region:COG0151F; Belongs to the GARS family. | 0.723 |
| fhs | purF | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch1189 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.825 |
| fhs | purH | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch3707 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Region:COG0138F. | 0.988 |
| fhs | purK | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch3207 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | N5-carboxyaminoimidazole ribonucleotide synthase PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.444 |
| fhs | purL | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch2006 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.800 |
| fhs | purM | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch1245 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine cyclo-ligase PurM; Region:COG0150F. | 0.430 |
| fhs | purN | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch1244 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.978 |
| fhs | purQ | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch2001 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.414 |
| fhs | purS | SAMCFNEI73_Ch2688 | SAMCFNEI73_Ch2000 | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.401 |
| purC | fhs | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch2688 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Formate--tetrahydrofolate ligase Fhs; Region:COG2759F; Belongs to the formate--tetrahydrofolate ligase family. | 0.867 |
| purC | purD | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch0899 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase PurD; Region:COG0151F; Belongs to the GARS family. | 0.993 |
| purC | purF | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch1189 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.975 |
| purC | purH | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch3707 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Region:COG0138F. | 0.988 |
| purC | purK | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch3207 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | N5-carboxyaminoimidazole ribonucleotide synthase PurK; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.996 |
| purC | purL | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch2006 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.964 |
| purC | purM | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch1245 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase PurM; Region:COG0150F. | 0.995 |
| purC | purN | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch1244 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.983 |
| purC | purQ | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch2001 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.979 |
| purC | purS | SAMCFNEI73_Ch1999 | SAMCFNEI73_Ch2000 | Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC; Region:COG0152F; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.985 |