Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APG90622.1Membrane efflux protein; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (371 aa)    
Predicted Functional Partners:
APG90623.1
Cation/multidrug efflux protein; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.970
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.909
tolC
TolC outer membrane protein; Region:COG1538M.
  
 0.853
APG90621.1
TetR family transcriptional regulator; Region:COG1309K.
 
   
 0.749
APG90624.1
TetR family transcriptional regulator; Region:COG1309K.
 
     0.674
macA
Macrolide-specific efflux protein MacA; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
  0.635
APG92101.1
RND family efflux transporter MFP subunit; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 
0.580
bepE
Efflux pump membrane transporter BepE; Region:COG0841V.
 
 
 0.567
bepG-2
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.549
bepG
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.545
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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