Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrBAspartate carbamoyltransferase PyrB; Region:COG0540F; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (313 aa)    
Predicted Functional Partners:
pyrC-2
Dihydroorotase PyrC; Region:COG0044F.
 0.999
carB
Carbamoyl-phosphate synthase large subunit; Region:COG0458EF; Belongs to the CarB family.
 
 0.999
carA
Carbamoyl-phosphate synthase small subunit; Region:COG0505EF; Belongs to the CarA family.
 
 0.999
pyrC
Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
   
 
 0.987
dht
D-hydantoinase/dihydropyrimidinase Dht; Region:COG0044F.
 
 0.977
pyrF
Orotidine 5'-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
  
 0.959
purA
Adenylosuccinate synthetase PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.958
pyrE
Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.952
APG92720.1
Xanthine-uracil permease; Region:COG2233F.
  
  
 0.921
argG
Argininosuccinate synthase ArgG; Region:COG0137E; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.914
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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