Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ntrBNitrogen regulation protein NtrB; Region:COG3852T. (382 aa)    
Predicted Functional Partners:
ntrC
Nitrogen assimilation regulatory protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.998
glnB
Nitrogen regulatory protein P-II; Region:COG0347TE; Belongs to the P(II) protein family.
  
 0.979
dus
tRNA-dihydrouridine synthase Dus; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.899
ntrX
Nitrogen assimilation regulatory protein NtrX; Region:COG2204T.
 
 
 0.856
amtB
Ammonia channel; Region:COG0004P.
  
 
 0.809
glnK
Nitrogen regulatory protein P-II; Region:COG0347TE; Belongs to the P(II) protein family.
  
 
 0.804
cya-7
Adenylate cyclase; Region:COG2114T.
 
 
 0.766
APG92287.1
Two-component response regulator transcriptional regulatory protein; Region:COG2204T.
 
 
 0.760
atoC
Acetoacetate metabolism regulatory protein AtoC; Region:COG2204T.
 
 
 0.740
ntrY
Nitrogen regulation protein NtrY; Region:COG5000T.
 
   
0.672
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.