Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
clsCardiolipin synthase Cls; Region:COG1502I. (487 aa)    
Predicted Functional Partners:
APG90673.1
Phospholipase D; Region:COG1502I.
  
  
 
0.927
APG90953.1
Hypothetical protein.
       0.567
ispD
Bifunctional enzyme IspD/IspF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
     
 0.520
mprF
Phosphatidylglycerol lysyltransferase MprF; Region:COG0392S.
  
  
 0.492
APG89897.1
Erythronolide synthase, modules 3 and 4; Region:COG0236IQ.
  
 
 0.489
xthA
Exodeoxyribonuclease III; Region:COG0708L.
       0.488
APG89892.1
Phosphosugar isomerase; Region:COG0517T; Belongs to the SIS family. GutQ/KpsF subfamily.
   
 0.457
APG90672.1
Endonuclease/exonuclease/phosphatase family protein; Region:COG3568R.
 
    0.435
gmk
Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP.
   
 0.433
pssA
CDP-diacylglycerol--serine O-phosphatidyltransferase; Region:COG1183I; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.425
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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