| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | cobD | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch2186 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.970 |
| cobB | cobE | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch2190 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | CobE protein CobE. | 0.887 |
| cobB | cobF | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3354 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6A synthase; Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. | 0.588 |
| cobB | cobH | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3352 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-8X methylmutase CobH; Region:COG2082H. | 0.994 |
| cobB | cobI | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3351 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-2 C(20)-methyltransferase CobI; Region:COG2243H; Belongs to the precorrin methyltransferase family. | 0.845 |
| cobB | cobJ | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3350 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-3B C(17)-methyltransferase CobJ; Region:COG1010H. | 0.877 |
| cobB | cobK | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3349 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6A reductase CobK; Region:COG2099H. | 0.817 |
| cobB | cobL | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3348 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6Y C(5,15)-methyltransferase; Region:COG2241H. | 0.898 |
| cobB | cobM | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch3347 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase CobM; Region:COG2875H; Belongs to the precorrin methyltransferase family. | 0.895 |
| cobB | cobN | SAMCFNEI73_Ch2188 | SAMCFNEI73_Ch2194 | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Aerobic cobaltochelatase subunit CobN; Region:COG1429H. | 0.980 |
| cobD | cobB | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch2188 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.970 |
| cobD | cobE | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch2190 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | CobE protein CobE. | 0.776 |
| cobD | cobH | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3352 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-8X methylmutase CobH; Region:COG2082H. | 0.897 |
| cobD | cobI | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3351 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Precorrin-2 C(20)-methyltransferase CobI; Region:COG2243H; Belongs to the precorrin methyltransferase family. | 0.679 |
| cobD | cobJ | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3350 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-3B C(17)-methyltransferase CobJ; Region:COG1010H. | 0.829 |
| cobD | cobK | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3349 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-6A reductase CobK; Region:COG2099H. | 0.649 |
| cobD | cobL | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3348 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-6Y C(5,15)-methyltransferase; Region:COG2241H. | 0.848 |
| cobD | cobM | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch3347 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Precorrin-4 C(11)-methyltransferase CobM; Region:COG2875H; Belongs to the precorrin methyltransferase family. | 0.833 |
| cobD | cobN | SAMCFNEI73_Ch2186 | SAMCFNEI73_Ch2194 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Aerobic cobaltochelatase subunit CobN; Region:COG1429H. | 0.558 |
| cobE | cobB | SAMCFNEI73_Ch2190 | SAMCFNEI73_Ch2188 | CobE protein CobE. | Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.887 |