STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
macAMacrolide-specific efflux protein MacA; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (419 aa)    
Predicted Functional Partners:
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.998
tolC
TolC outer membrane protein; Region:COG1538M.
 
 
 0.688
bepE
Efflux pump membrane transporter BepE; Region:COG0841V.
 
 
 0.613
acrF
Acriflavine resistance protein F; Region:COG0841V.
 
 
 0.607
bepG-2
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.578
bepG
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.530
APG91705.1
Transporter; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.511
nolG
Nodulation protein NolG; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.499
APG91632.1
TetR family transcriptional regulator; Region:COG1309K.
       0.463
APG90623.1
Cation/multidrug efflux protein; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.436
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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