STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdtAMultidrug resistance protein MdtA; Region:COG0845MV; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (396 aa)    
Predicted Functional Partners:
macB
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.974
APG91705.1
Transporter; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.964
tolC
TolC outer membrane protein; Region:COG1538M.
 
 
 0.683
bepG-2
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.589
bepG
Efflux pump membrane transporter BepG; Region:COG0841V.
 
 
 0.587
acrF
Acriflavine resistance protein F; Region:COG0841V.
 
 
 0.572
APG91707.1
Hypothetical protein.
       0.572
bepE
Efflux pump membrane transporter BepE; Region:COG0841V.
 
 
 0.569
nolG
Nodulation protein NolG; Region:COG0841V; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.484
lolD
Lipoprotein-releasing system ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
  
 
 0.411
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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