Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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acoDAcetaldehyde dehydrogenase 2; Region:COG1012C; Belongs to the aldehyde dehydrogenase family. (536 aa)    
Predicted Functional Partners:
adhI
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.913
adhI-2
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.913
adhI-3
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
 0.913
adhA
Alcohol dehydrogenase AdhA; Region:COG1064G.
  
 0.912
adhA-2
Alcohol dehydrogenase AdhA; Region:COG1064G.
  
 0.912
adhC
NADP-dependent alcohol dehydrogenase C 2; Region:COG1064G.
  
 0.912
ald-3
Aldehyde dehydrogenase; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.911
adhA-3
Alcohol dehydrogenase; Region:COG1064G.
   
  0.911
APG92268.1
acetyl-CoA synthetase; Region:COG0365I.
   
 0.911
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.911
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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