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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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aptAdenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (197 aa)    
Predicted Functional Partners:
purB
Adenylosuccinate lyase PurB; Region:COG0015F; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.968
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Region:COG0138F.
  
 0.960
punA
Purine nucleoside phosphorylase 1; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.947
adk
Adenylate kinase Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.936
surE
Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.922
amn
AMP nucleosidase Amn; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
   
 0.919
ade
Adenine deaminase 1; Region:COG1001F; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
 0.915
APG91918.1
Laccase domain-containing protein; Region:COG1496P; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.909
APG92489.1
5'-nucleotidase; Region:COG0737FV; Belongs to the 5'-nucleotidase family.
    
 0.909
mazG
Nucleoside triphosphate pyrophosphohydrolase MazG; Region:COG3956R.
    
  0.903
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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