STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (337 aa)    
Predicted Functional Partners:
bioD
ATP-dependent dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.999
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Region:COG0161H; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.992
bioF-2
8-amino-7-oxononanoate synthase BioF; Region:COG0156H.
  
 0.971
birA
Biotin transcriptional regulator bifunctional protein BirA; Region:COG0340H.
  
 
 0.937
APG92924.1
Omega-amino acid--pyruvate aminotransferase; Region:COG0161H; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.824
APG91979.1
Omega-amino acid--pyruvate aminotransferase; Region:COG0161H; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.821
fabH-2
3-oxoacyl-ACP synthase; Region:COG0332I.
  
  
 0.817
bioF
8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase; Region:COG0156H.
 
  
 0.700
kbl
2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
 
  
 0.700
hemA
5-aminolevulinate synthase; Region:COG0156H.
 
  
 0.700
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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