STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ald-3Aldehyde dehydrogenase; Region:COG1012C; Belongs to the aldehyde dehydrogenase family. (477 aa)    
Predicted Functional Partners:
APG92268.1
acetyl-CoA synthetase; Region:COG0365I.
   
 0.929
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.929
mmsA
Methylmalonate-semialdehyde dehydrogenase; Region:COG1012C.
  
  
 
0.922
fadB-2
3-hydroxyacyl-CoA dehydrogenase; Region:COG1024I.
  
 0.920
prr
Gamma-aminobutyraldehyde dehydrogenase Prr; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.918
ackA
Acetate kinase AckA; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
 
 0.917
adhI
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.914
adhI-2
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.914
adhI-3
Alcohol dehydrogenase class-3; Region:COG1062R; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
 
 0.914
APG91389.1
3-hydroxyisobutyrate dehydrogenase; Region:COG2084I.
  
 
 0.912
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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