STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdeA-2Methionine gamma-lyase MdeA; Region:COG0626E. (390 aa)    
Predicted Functional Partners:
lutR
HTH-type transcriptional regulator LutR; Region:COG2186K.
 
     0.836
APG92154.1
Sugar ABC transporter sugar-binding protein; Region:COG1653G.
 
     0.730
metH-3
Methionine synthase MetH; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.715
cysK
Cysteine synthase A.
 
 
 0.692
cysK-2
Cysteine synthase A; Region:COG0031E.
 
 
 0.665
metF
5,10-methylenetetrahydrofolate reductase; Region:COG0685E; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.619
APG91506.1
Bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase; Region:COG0685E; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.605
metA
Homoserine O-succinyltransferase MetA; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
  
 0.572
APG91505.1
Zinc-finger protein.
  
 
 0.560
puuB
Gamma-glutamylputrescine oxidoreductase PuuB; Region:COG0665E.
     
 0.526
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
Server load: low (32%) [HD]