| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APG89897.1 | APG91014.1 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch1721 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 0.603 |
| APG89897.1 | APG92824.1 | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch3574 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 0.552 |
| APG89897.1 | grxC | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2009 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Monothiol glutaredoxin; Region:COG0278O; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.512 |
| APG89897.1 | prmC | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2980 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.525 |
| APG89897.1 | ubiA | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0904 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.625 |
| APG89897.1 | ubiE | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch0368 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.462 |
| APG89897.1 | ubiG | SAMCFNEI73_Ch0569 | SAMCFNEI73_Ch2986 | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.553 |
| APG90885.1 | APG91014.1 | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch1721 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 0.492 |
| APG90885.1 | APG92824.1 | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch3574 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 0.462 |
| APG90885.1 | ubiA | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch0904 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.549 |
| APG90885.1 | ubiB | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch0367 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.748 |
| APG90885.1 | ubiE | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch0368 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.423 |
| APG90885.1 | ubiG | SAMCFNEI73_Ch1584 | SAMCFNEI73_Ch2986 | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.672 |
| APG91014.1 | APG89897.1 | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch0569 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | Erythronolide synthase, modules 3 and 4; Region:COG0236IQ. | 0.603 |
| APG91014.1 | APG90885.1 | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch1584 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | Oligoketide cyclase/lipid transport protein; Region:COG2867J. | 0.492 |
| APG91014.1 | APG92824.1 | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch3574 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 0.923 |
| APG91014.1 | grxC | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch2009 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | Monothiol glutaredoxin; Region:COG0278O; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.440 |
| APG91014.1 | ubiA | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch0904 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.652 |
| APG91014.1 | ubiB | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch0367 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.694 |
| APG91014.1 | ubiE | SAMCFNEI73_Ch1721 | SAMCFNEI73_Ch0368 | 2-octaprenyl-6-methoxyphenyl hydroxylase; Region:COG0654HC. | Ubiquinone/menaquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.939 |