STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (455 aa)    
Predicted Functional Partners:
maiA
Maleylacetoacetate isomerase MaiA; Region:COG0625O.
 
 
 0.997
hpd
4-hydroxyphenylpyruvate dioxygenase; Region:COG3185ER.
 
 0.997
APG92631.1
Fumarylacetoacetate hydrolase family protein; Region:COG0179Q.
 
  
 0.968
APG92634.1
MarR family transcriptional regulator; Region:COG1846K.
 
     0.874
APG91424.1
Fumarylpyruvate hydrolase protein; Region:COG0179Q.
  
  
 0.813
APG92632.1
Hydrolase; Region:COG1234J.
       0.798
phhB
Pterin-4-alpha-carbinolamine dehydratase; Region:COG2154H.
  
  
 0.661
purU
Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.460
paaN
Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Region:COG1012C.
   
  
 0.435
mhqA
Ring-cleaving dioxygenase MhqA; Region:COG0346Q.
     
 0.431
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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