Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
hmgAHomogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. (455 aa)    
Predicted Functional Partners:
maiA
Maleylacetoacetate isomerase MaiA; Region:COG0625O.
 
 
 0.998
hpd
4-hydroxyphenylpyruvate dioxygenase; Region:COG3185ER.
 
 0.997
APG92631.1
Fumarylacetoacetate hydrolase family protein; Region:COG0179Q.
 
  
 0.962
APG92634.1
MarR family transcriptional regulator; Region:COG1846K.
 
     0.899
APG92632.1
Hydrolase; Region:COG1234J.
       0.809
APG91424.1
Fumarylpyruvate hydrolase protein; Region:COG0179Q.
  
  
 0.728
phhB
Pterin-4-alpha-carbinolamine dehydratase; Region:COG2154H.
  
  
 0.670
purU
Formyltetrahydrofolate deformylase PurU; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
       0.460
fadB
enoyl-CoA hydratase FadB; Region:COG1024I; Belongs to the enoyl-CoA hydratase/isomerase family.
   
  
 0.440
APG92929.1
3-hydroxypropionyl-coenzyme A dehydratase; Region:COG1024I.
   
  
 0.440
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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