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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amtBAmmonia channel; Region:COG0004P. (474 aa)    
Predicted Functional Partners:
glnK
Nitrogen regulatory protein P-II; Region:COG0347TE; Belongs to the P(II) protein family.
 
 0.999
glnB
Nitrogen regulatory protein P-II; Region:COG0347TE; Belongs to the P(II) protein family.
 
 0.998
ntrB
Nitrogen regulation protein NtrB; Region:COG3852T.
  
 
 0.756
gltB-2
Ferredoxin-dependent glutamate synthase 1; Region:COG0067E.
 
  
 0.732
acnA
Aconitate hydratase AcnA; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 
 0.559
nadE
Glutamine-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.518
pleC
Non-motile and phage-resistance protein PleC; Region:COG0591E.
  
 
 0.504
glnD
[protein-PII] uridylyltransferase GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.476
tesB
acyl-CoA thioesterase; Region:COG1946I.
       0.450
glnA
Glutamine synthetase; Region:COG0174E.
  
  
 0.447
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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