STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
acnAAconitate hydratase AcnA; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (896 aa)    
Predicted Functional Partners:
gltA
Citrate synthase GltA; Region:COG0372C; Belongs to the citrate synthase family.
 
 0.999
icd
Isocitrate dehydrogenase; Region:COG0538C; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.995
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.959
aceA
Isocitrate lyase AceA; Region:COG2224C.
   
 
 0.939
fadB-2
3-hydroxyacyl-CoA dehydrogenase; Region:COG1024I.
   
 0.907
APG92181.1
enoyl-CoA hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase; Region:COG1024I.
   
 0.907
mdh-3
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 0.899
sodB
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.878
atpA
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
   
 0.873
sdhB
Succinate dehydrogenase iron-sulfur subunit SdhB; Region:COG0479C; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.873
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
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