Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
afr1,5-anhydro-D-fructose reductase; Region:COG0673R. (333 aa)    
Predicted Functional Partners:
APG92928.1
Coenzyme A transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
 
     0.889
purR-2
HTH-type transcriptional repressor PurR; Region:COG1609K.
 
     0.836
APG92929.1
3-hydroxypropionyl-coenzyme A dehydratase; Region:COG1024I.
 
     0.817
dhaS
Aldehyde dehydrogenase DhaS; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
 
    0.809
APG92937.1
Dehydrogenase; Region:COG2303IR.
 
    0.702
APG92925.1
Hypothetical protein; Region:COG0329EM.
 
     0.593
lysS
lysine--tRNA ligase LysS; Region:COG1190J; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.568
APG92779.1
Hypothetical protein.
  
    0.469
iolB
5-deoxy-glucuronate isomerase IolB; Region:COG3718G.
 
  
 0.443
iolC
5-dehydro-2-deoxygluconokinase IolC; Region:COG0524G.
 
  
 0.441
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.