STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttuDHydroxypyruvate reductase TtuD; Region:COG2379G. (423 aa)    
Predicted Functional Partners:
gyaR
Glyoxylate reductase GyaR; Region:COG1052CHR; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.949
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.944
ghrA
Glyoxylate/hydroxypyruvate reductase A; Region:COG0111HR.
    
 0.906
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
 0.901
ald-3
Aldehyde dehydrogenase; Region:COG1012C; Belongs to the aldehyde dehydrogenase family.
     
 0.901
gpmB-2
Phosphoglycerate kinase; Region:COG0406G.
     
  0.900
pyk
Pyruvate kinase Pyk; Region:COG0469G; Belongs to the pyruvate kinase family.
 
 
 0.873
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
    
 0.824
ppdK
Pyruvate, phosphate dikinase; Region:COG0574G; Belongs to the PEP-utilizing enzyme family.
    
  0.819
pgi
Glucose-6-phosphate isomerase; Region:COG0166G; Belongs to the GPI family.
    
 0.816
Your Current Organism:
Sinorhizobium americanum
NCBI taxonomy Id: 194963
Other names: ATCC BAA-532, CIP 108390, DSM 15007, Ensifer americanum, Ensifer americanus, Ensifer americanus corrig. (Toledo et al. 2003) Wang et al. 2015, Ensifer sp. AC14c, Ensifer sp. CFNEI 156, S. americanum, Sinorhizobium americanum Toledo et al. 2004, Sinorhizobium americanus, Sinorhizobium sp. CFNEI 156, Sinorhizobium sp. CFNEI 54, strain CFNEI 156
Server load: low (38%) [HD]