| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aldA | tdcB | ATE51_03224 | ATE51_01986 | Lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | L-threonine dehydratase catabolic TdcB. | 0.832 |
| aldA | tdcG | ATE51_03224 | ATE51_00280 | Lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.839 |
| aldA | trpA | ATE51_03224 | ATE51_03514 | Lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.849 |
| aldA | trpB | ATE51_03224 | ATE51_03516 | Lactaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.819 |
| cysE | glyA | ATE51_02122 | ATE51_03410 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.846 |
| cysE | pcs | ATE51_02122 | ATE51_01372 | Serine acetyltransferase. | Phosphatidylcholine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.800 |
| cysE | serB | ATE51_02122 | ATE51_03664 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.829 |
| cysE | tdcB | ATE51_02122 | ATE51_01986 | Serine acetyltransferase. | L-threonine dehydratase catabolic TdcB. | 0.803 |
| cysE | tdcG | ATE51_02122 | ATE51_00280 | Serine acetyltransferase. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.912 |
| cysE | thrB | ATE51_02122 | ATE51_04194 | Serine acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.827 |
| cysE | trpA | ATE51_02122 | ATE51_03514 | Serine acetyltransferase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.803 |
| cysE | trpB | ATE51_02122 | ATE51_03516 | Serine acetyltransferase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.803 |
| glyA | cysE | ATE51_03410 | ATE51_02122 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine acetyltransferase. | 0.846 |
| glyA | pcs | ATE51_03410 | ATE51_01372 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphatidylcholine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | serB | ATE51_03410 | ATE51_03664 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.923 |
| glyA | tdcB | ATE51_03410 | ATE51_01986 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-threonine dehydratase catabolic TdcB. | 0.930 |
| glyA | tdcG | ATE51_03410 | ATE51_00280 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.962 |
| glyA | trpA | ATE51_03410 | ATE51_03514 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.934 |
| glyA | trpB | ATE51_03410 | ATE51_03516 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.930 |
| pcs | cysE | ATE51_01372 | ATE51_02122 | Phosphatidylcholine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Serine acetyltransferase. | 0.800 |