Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vacAVacuolating cytotoxin autotransporter precursor. (757 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
      
 0.776
flaA_2
Flagellin A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.668
flaA_1
Flagellin A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.667
flaA_3
Flagellin A; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.667
rdxA
Putative NAD(P)H nitroreductase.
      
 0.650
trpC_1
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
     
 0.650
slt
Soluble lytic murein transglycosylase precursor.
      
 0.633
flaB2
Flagellar filament 31.3 kDa core protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
    
 
 0.506
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.469
mutY
A/G-specific adenine glycosylase.
  
  
 0.456
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
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