| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdtA | cdtB | ATE51_03644 | ATE51_03646 | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | Cytolethal distending toxin subunit B precursor. | 0.998 |
| cdtA | dnaJ | ATE51_03644 | ATE51_02390 | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.776 |
| cdtA | gyrA | ATE51_03644 | ATE51_01566 | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.775 |
| cdtA | recR | ATE51_03644 | ATE51_02396 | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.450 |
| cdtA | yclQ | ATE51_03644 | ATE51_00854 | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | Putative ABC transporter solute-binding protein YclQ precursor. | 0.778 |
| cdtB | cdtA | ATE51_03646 | ATE51_03644 | Cytolethal distending toxin subunit B precursor. | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | 0.998 |
| cdtB | dnaJ | ATE51_03646 | ATE51_02390 | Cytolethal distending toxin subunit B precursor. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.774 |
| cdtB | gyrA | ATE51_03646 | ATE51_01566 | Cytolethal distending toxin subunit B precursor. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.780 |
| cdtB | recR | ATE51_03646 | ATE51_02396 | Cytolethal distending toxin subunit B precursor. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.450 |
| cdtB | yclQ | ATE51_03646 | ATE51_00854 | Cytolethal distending toxin subunit B precursor. | Putative ABC transporter solute-binding protein YclQ precursor. | 0.778 |
| cirA_2 | yclQ | ATE51_02138 | ATE51_00854 | Colicin I receptor precursor. | Putative ABC transporter solute-binding protein YclQ precursor. | 0.775 |
| dnaJ | cdtA | ATE51_02390 | ATE51_03644 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Cytolethal distending toxin subunit A precursor; CDTs are cytotoxins. | 0.776 |
| dnaJ | cdtB | ATE51_02390 | ATE51_03646 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Cytolethal distending toxin subunit B precursor. | 0.774 |
| dnaJ | gyrA | ATE51_02390 | ATE51_01566 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.781 |
| dnaJ | recR | ATE51_02390 | ATE51_02396 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.885 |
| dnaJ | yclQ | ATE51_02390 | ATE51_00854 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Putative ABC transporter solute-binding protein YclQ precursor. | 0.774 |
| feuB_1 | feuB_2 | ATE51_00858 | ATE51_00860 | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.991 |
| feuB_1 | fhuC_2 | ATE51_00858 | ATE51_00856 | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron(3+)-hydroxamate import ATP-binding protein FhuC. | 0.997 |
| feuB_1 | yclQ | ATE51_00858 | ATE51_00854 | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative ABC transporter solute-binding protein YclQ precursor. | 0.993 |
| feuB_2 | feuB_1 | ATE51_00860 | ATE51_00858 | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron-uptake system permease protein FeuB; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.991 |
