Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
czcDCadmium, cobalt and zinc/H(+)-K(+) antiporter. (313 aa)    
Predicted Functional Partners:
copA_1
Copper-exporting P-type ATPase A.
  
  
 0.910
ALU99173.1
Hypothetical protein.
     
 0.833
czcB
Cobalt-zinc-cadmium resistance protein CzcB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.768
ALU99171.1
Hypothetical protein.
     
 0.593
kefC
Glutathione-regulated potassium-efflux system protein KefC; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
      
 0.587
mcp4_2
Methyl-accepting chemotaxis protein 4.
      
 0.580
zupT
Zinc transporter ZupT; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
 
 0.512
ALU99336.1
Zinc transporter.
      
 0.504
fieF
Ferrous-iron efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
0.504
nnr
Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family.
     
 0.499
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
Server load: low (14%) [HD]