STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
hldEBifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (461 aa)    
Predicted Functional Partners:
gmhA1
Phosphoheptose isomerase 1; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.999
gmhB
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase.
  
 0.998
hldD
ADP-L-glycero-D-manno-heptose-6-epimerase.
 
 
 0.993
rfaF
ADP-heptose--LPS heptosyltransferase 2.
 
  
 0.890
rfaC
Lipopolysaccharide heptosyltransferase 1.
 
  
 0.855
cyf_2
Cytochrome c-553 precursor.
       0.572
kdsC
3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC.
      0.533
rpiB
Ribose-5-phosphate isomerase B.
 
      0.467
hisB
Histidine biosynthesis bifunctional protein HisB; In the N-terminal section; belongs to the histidinol- phosphatase family.
  
  
 0.463
waaA
3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.423
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
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