| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| coaD | cysE | ATE51_02114 | ATE51_02122 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Serine acetyltransferase. | 0.817 |
| coaD | tmk_1 | ATE51_02114 | ATE51_02116 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.834 |
| cysE | coaD | ATE51_02122 | ATE51_02114 | Serine acetyltransferase. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.817 |
| cysE | cysK | ATE51_02122 | ATE51_01724 | Serine acetyltransferase. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.998 |
| cysE | cysS | ATE51_02122 | ATE51_02040 | Serine acetyltransferase. | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.985 |
| cysE | glyA | ATE51_02122 | ATE51_03410 | Serine acetyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.840 |
| cysE | hom | ATE51_02122 | ATE51_03952 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.842 |
| cysE | serB | ATE51_02122 | ATE51_03664 | Serine acetyltransferase. | Phosphoserine phosphatase. | 0.826 |
| cysE | tdcB | ATE51_02122 | ATE51_01986 | Serine acetyltransferase. | L-threonine dehydratase catabolic TdcB. | 0.822 |
| cysE | tdcG | ATE51_02122 | ATE51_00280 | Serine acetyltransferase. | L-serine dehydratase TdcG; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
| cysE | thrB | ATE51_02122 | ATE51_04194 | Serine acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.822 |
| cysE | tmk_1 | ATE51_02122 | ATE51_02116 | Serine acetyltransferase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.817 |
| cysK | cysE | ATE51_01724 | ATE51_02122 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Serine acetyltransferase. | 0.998 |
| cysK | cysS | ATE51_01724 | ATE51_02040 | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.924 |
| cysS | cysE | ATE51_02040 | ATE51_02122 | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Serine acetyltransferase. | 0.985 |
| cysS | cysK | ATE51_02040 | ATE51_01724 | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.924 |
| cysS | glyA | ATE51_02040 | ATE51_03410 | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.410 |
| glyA | cysE | ATE51_03410 | ATE51_02122 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine acetyltransferase. | 0.840 |
| glyA | cysS | ATE51_03410 | ATE51_02040 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cysteine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.410 |
| glyA | serB | ATE51_03410 | ATE51_03664 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.922 |