hypF protein (Campylobacter coli) - STRING interaction network

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hypF

Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (728 aa)

Predicted Functional Partners:

hypE

0.988

hypD

0.950

hypB

0.949

hypC

0.896

hypA

0.848

hybD

0.848

ALU99692.1

0.817

carB

0.795

fdnG

0.774

ALU99693.1

0.648

Your Current Organism:

Campylobacter coli

NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALU99692.1	ALU99693.1	ATE51_02346	ATE51_02348	Hypothetical protein.	Hypothetical protein.	0.648
ALU99692.1	hypA	ATE51_02346	ATE51_02334	Hypothetical protein.	Hydrogenase/urease nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.670
ALU99692.1	hypB	ATE51_02346	ATE51_02342	Hypothetical protein.	Hydrogenase isoenzymes nickel incorporation protein HypB.	0.683
ALU99692.1	hypC	ATE51_02346	ATE51_02340	Hypothetical protein.	Hydrogenase isoenzymes formation protein HypC.	0.726
ALU99692.1	hypD	ATE51_02346	ATE51_02338	Hypothetical protein.	Hydrogenase expression/formation protein HypD; Belongs to the HypD family.	0.723
ALU99692.1	hypE	ATE51_02346	ATE51_02336	Hypothetical protein.	Hydrogenase isoenzymes formation protein HypE.	0.938
ALU99692.1	hypF	ATE51_02346	ATE51_02344	Hypothetical protein.	Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.	0.817
ALU99693.1	ALU99692.1	ATE51_02348	ATE51_02346	Hypothetical protein.	Hypothetical protein.	0.648
ALU99693.1	hypA	ATE51_02348	ATE51_02334	Hypothetical protein.	Hydrogenase/urease nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.474
ALU99693.1	hypB	ATE51_02348	ATE51_02342	Hypothetical protein.	Hydrogenase isoenzymes nickel incorporation protein HypB.	0.474
ALU99693.1	hypC	ATE51_02348	ATE51_02340	Hypothetical protein.	Hydrogenase isoenzymes formation protein HypC.	0.482
ALU99693.1	hypD	ATE51_02348	ATE51_02338	Hypothetical protein.	Hydrogenase expression/formation protein HypD; Belongs to the HypD family.	0.474
ALU99693.1	hypE	ATE51_02348	ATE51_02336	Hypothetical protein.	Hydrogenase isoenzymes formation protein HypE.	0.474
ALU99693.1	hypF	ATE51_02348	ATE51_02344	Hypothetical protein.	Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.	0.648
carB	hypF	ATE51_03670	ATE51_02344	Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.	Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.	0.795
fdnG	hybD	ATE51_00546	ATE51_02398	Formate dehydrogenase, nitrate-inducible, major subunit precursor.	Hydrogenase 2 maturation protease.	0.805
fdnG	hypB	ATE51_00546	ATE51_02342	Formate dehydrogenase, nitrate-inducible, major subunit precursor.	Hydrogenase isoenzymes nickel incorporation protein HypB.	0.652
fdnG	hypF	ATE51_00546	ATE51_02344	Formate dehydrogenase, nitrate-inducible, major subunit precursor.	Carbamoyltransferase HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.	0.774
hybD	fdnG	ATE51_02398	ATE51_00546	Hydrogenase 2 maturation protease.	Formate dehydrogenase, nitrate-inducible, major subunit precursor.	0.805
hybD	hypA	ATE51_02398	ATE51_02334	Hydrogenase 2 maturation protease.	Hydrogenase/urease nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.	0.549

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