Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
macAMacrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (390 aa)    
Predicted Functional Partners:
macB_3
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.999
cusC
Cation efflux system protein CusC precursor.
 
 0.976
bepE
Efflux pump membrane transporter BepE.
 
 
 0.864
ttgC
Toluene efflux pump outer membrane protein TtgC precursor.
 
 
 0.786
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
      
 0.772
ALU99313.1
Outer membrane efflux protein.
  
 0.767
mdtC
Multidrug resistance protein MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 0.766
czcB
Cobalt-zinc-cadmium resistance protein CzcB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
  
 0.638
lpoB
Hypothetical protein.
     
 0.603
rpoBC_2
Bifunctional DNA-directed RNA polymerase subunit beta-beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  
 0.555
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
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