Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
icd2Isocitrate dehydrogenase [NADP] 2; Belongs to the monomeric-type IDH family. (734 aa)    
Predicted Functional Partners:
oorC
2-oxoglutarate-acceptor oxidoreductase subunit OorC.
  
 
 0.997
korA
2-oxoglutarate oxidoreductase subunit KorA.
  
 
 0.997
hydA_3
Periplasmic [Fe] hydrogenase large subunit.
  
 
 0.993
mdh
Malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
  
 0.989
korB
2-oxoglutarate oxidoreductase subunit KorB.
  
 
 0.988
acnB
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
   
 
 0.932
ldh
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
  
 0.879
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.876
sucC
Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.863
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
     
 0.860
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
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