Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ttgCToluene efflux pump outer membrane protein TtgC precursor. (492 aa)    
Predicted Functional Partners:
mdtE
Multidrug resistance protein MdtE precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 0.999
bepE
Efflux pump membrane transporter BepE.
 0.999
mdtC
Multidrug resistance protein MdtC; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 0.965
ALU99313.1
Outer membrane efflux protein.
  
  
 0.951
qacR
HTH-type transcriptional regulator QacR.
 
   
 0.927
czcB
Cobalt-zinc-cadmium resistance protein CzcB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.924
macB_3
Macrolide export ATP-binding/permease protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.861
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.829
macA
Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.786
ALV00247.1
Ubp3 associated protein Bre5.
       0.615
Your Current Organism:
Campylobacter coli
NCBI taxonomy Id: 195
Other names: ATCC 33559, C. coli, CCUG 11283, CCUG 14540, CCUG:33450 [[Campylobacter hyoilei]], CIP 70.80, CIP 7080, Campylobacter hyoilei, Campylobacter sp. OH-18-18281-4B, Campylobacter sp. OH-18-7816, DSM 4689, JCM 2529, LMG 6440, LMG 9860, LMG:6440, LMG:9860, NCTC 11366, Vibrio coli, strain RMIT 32A [[Campylobacter hyoilei]]
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