| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCO0139 | glyA | ATE51_00170 | ATE51_03410 | Aspartate racemase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.900 |
| CCO0139 | serB | ATE51_00170 | ATE51_03664 | Aspartate racemase. | Phosphoserine phosphatase. | 0.900 |
| CCO0139 | tdcB | ATE51_00170 | ATE51_01986 | Aspartate racemase. | L-threonine dehydratase catabolic TdcB. | 0.900 |
| CCO0139 | trpA | ATE51_00170 | ATE51_03514 | Aspartate racemase. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.900 |
| CCO0139 | trpB | ATE51_00170 | ATE51_03516 | Aspartate racemase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
| glyA | CCO0139 | ATE51_03410 | ATE51_00170 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aspartate racemase. | 0.900 |
| glyA | pabB | ATE51_03410 | ATE51_01782 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Aminodeoxychorismate synthase component 1. | 0.472 |
| glyA | serB | ATE51_03410 | ATE51_03664 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine phosphatase. | 0.922 |
| glyA | tdcB | ATE51_03410 | ATE51_01986 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-threonine dehydratase catabolic TdcB. | 0.920 |
| glyA | trpA | ATE51_03410 | ATE51_03514 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.926 |
| glyA | trpB | ATE51_03410 | ATE51_03516 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.920 |
| pabB | glyA | ATE51_01782 | ATE51_03410 | Aminodeoxychorismate synthase component 1. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.472 |
| pabB | tdcB | ATE51_01782 | ATE51_01986 | Aminodeoxychorismate synthase component 1. | L-threonine dehydratase catabolic TdcB. | 0.635 |
| pabB | trpA | ATE51_01782 | ATE51_03514 | Aminodeoxychorismate synthase component 1. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.973 |
| pabB | trpB | ATE51_01782 | ATE51_03516 | Aminodeoxychorismate synthase component 1. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.973 |
| pabB | trpC_1 | ATE51_01782 | ATE51_03206 | Aminodeoxychorismate synthase component 1. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.972 |
| pabB | trpC_2 | ATE51_01782 | ATE51_03518 | Aminodeoxychorismate synthase component 1. | Tryptophan biosynthesis protein TrpCF; Belongs to the TrpF family. | 0.928 |
| pabB | trpE | ATE51_01782 | ATE51_03522 | Aminodeoxychorismate synthase component 1. | Anthranilate synthase component 1. | 0.899 |
| pabB | trpGD | ATE51_01782 | ATE51_03520 | Aminodeoxychorismate synthase component 1. | Bifunctional protein TrpGD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
| serB | CCO0139 | ATE51_03664 | ATE51_00170 | Phosphoserine phosphatase. | Aspartate racemase. | 0.900 |
