node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFM26412.1 | SFM26609.1 | SAMN05421721_101241 | SAMN05421721_101256 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Glutamate synthase (NADH) large subunit. | 0.994 |
SFM26412.1 | SFM33876.1 | SAMN05421721_101241 | SAMN05421721_10357 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Acetolactate synthase, large subunit. | 0.993 |
SFM26412.1 | SFM33883.1 | SAMN05421721_101241 | SAMN05421721_10358 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Acetolactate synthase, small subunit. | 0.964 |
SFM26412.1 | SFM38552.1 | SAMN05421721_101241 | SAMN05421721_10492 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Homocitrate synthase NifV; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.987 |
SFM26412.1 | SFM57720.1 | SAMN05421721_101241 | SAMN05421721_11134 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.928 |
SFM26412.1 | ilvC | SAMN05421721_101241 | SAMN05421721_10359 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.557 |
SFM26412.1 | leuA | SAMN05421721_101241 | SAMN05421721_10588 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.987 |
SFM26412.1 | leuB | SAMN05421721_101241 | SAMN05421721_12017 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.953 |
SFM26412.1 | leuC | SAMN05421721_101241 | SAMN05421721_12019 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.950 |
SFM26412.1 | leuD | SAMN05421721_101241 | SAMN05421721_12018 | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.921 |
SFM26609.1 | SFM26412.1 | SAMN05421721_101256 | SAMN05421721_101241 | Glutamate synthase (NADH) large subunit. | Pyruvate-ferredoxin/flavodoxin oxidoreductase. | 0.994 |
SFM26609.1 | SFM33876.1 | SAMN05421721_101256 | SAMN05421721_10357 | Glutamate synthase (NADH) large subunit. | Acetolactate synthase, large subunit. | 0.803 |
SFM26609.1 | SFM33883.1 | SAMN05421721_101256 | SAMN05421721_10358 | Glutamate synthase (NADH) large subunit. | Acetolactate synthase, small subunit. | 0.918 |
SFM26609.1 | SFM38552.1 | SAMN05421721_101256 | SAMN05421721_10492 | Glutamate synthase (NADH) large subunit. | Homocitrate synthase NifV; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.530 |
SFM26609.1 | SFM57720.1 | SAMN05421721_101256 | SAMN05421721_11134 | Glutamate synthase (NADH) large subunit. | Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.439 |
SFM26609.1 | ilvC | SAMN05421721_101256 | SAMN05421721_10359 | Glutamate synthase (NADH) large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.938 |
SFM26609.1 | leuA | SAMN05421721_101256 | SAMN05421721_10588 | Glutamate synthase (NADH) large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.530 |
SFM26609.1 | leuB | SAMN05421721_101256 | SAMN05421721_12017 | Glutamate synthase (NADH) large subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.987 |
SFM26609.1 | leuC | SAMN05421721_101256 | SAMN05421721_12019 | Glutamate synthase (NADH) large subunit. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.905 |
SFM26609.1 | leuD | SAMN05421721_101256 | SAMN05421721_12018 | Glutamate synthase (NADH) large subunit. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.861 |