STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sbcDProbable exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (407 aa)    
Predicted Functional Partners:
sbcC
Probable exonuclease; 1175 aa, similar to >gp:CPSBCC_1 sbcC gene product from Clostridium perfringens (140 aa); 91.4% identity in 140 aa overlap; CPE0216.
 
 0.998
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.988
addA
ATP-dependent deoxyribonuclease chain A; The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities; Belongs to the helicase family. AddA subfamily.
 
  
 0.882
CPE0818
endo-beta-N-acetylglucosaminidase; 1127 aa, similar to gpu:AP001509_223 endo-beta-N-acetylglucosaminidase from Bacillus halodurans (878 aa); 42.5% identity in 656 aa overlap. Putative N-terminal signal sequence was found by PSORT.
  
 0.875
recQ
724 aa, similar to pir:F69901 DNA helicase recQ from Bacillus subtilis (591 aa); 48.1% identity in 590 aa overlap. 1 putative transmembrane region was found by PSORT; CPE0343.
  
 0.706
CPE1197
781 aa, similar to pir:B71116 probable helicase protein PH0697 from Pyrococcus horikoshii (641 aa); 28.3% identity in 594 aa overlap. 1 putative transmembrane region was found by PSORT.
  
 0.704
recQ-2
592 aa, similar to pir:F69901 DNA helicase recQ from Bacillus subtilis (591 aa); 38% identity in 587 aa overlap; CPE1335.
  
 0.689
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.688
CPE0674
361 aa, partially similar to pir:F75357 hypothetical protein from Deinococcus radiodurans (strain R1) (328 aa); 26% identity in 181 aa overlap.Also similar to many DNA helicases.
  
 0.667
CPE1480
Probable sulfate permease; 551 aa, similar to gpu:AE004350_10 sulfate permease family protein from Vibrio cholera (553 aa); 43.4% identity in 535 aa overlap. 10 putative transmembrane regions were found by PSORT.
  
   0.613
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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