STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CPE0594Hypothetical protein; 157 aa, similar to C-terminal of gpu:AE004122_1 MutT/nudix family protein from Vibrio cholerae (269 aa); 32.1% identity in 162 aa overlap. (157 aa)    
Predicted Functional Partners:
CPE0256
Probable transcriptional regulator; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily.
  
 
  0.918
CPE1207
Conserved hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.915
cinA
412 aa, similar to sp:CINA_BACSU PUTATIVE COMPETENCE-DAMAGE PROTEIN from Bacillus subtilis (416 aa); 43.1% identity in 394 aa overlap; CPE0132; Belongs to the CinA family.
    
 0.913
CPE1058
553 aa, similar to pir:D70680 hypothetical protein Rv2438c from Mycobacterium tuberculosis (strain H37RV) (738 aa); 42% identity in 581 aa overlap. 1 putative transmembrane region was found by PSORT; Belongs to the NAD synthetase family.
  
 
 0.910
cpdB
1181 aa, similar to gp:AB028630_4 2', 3'-cyclic nucleotide 2'-phosphodiesterase from Clostridium perfringens (865 aa); 65.7% identity in 867 aa overlap. Putative N-terminal signal sequence and 2 putative transmembrane regions were found by PSORT; CPE1950.
    
  0.903
cpdA
1215 aa, similar to gp:AB028630_4 2', 3'-cyclic nucleotide 2'-phosphodiesterase from Clostridium perfringens (865 aa); 99.9% identity in 865 aa overlap. Putative N-terminal signal sequence and 1 putative transmembrane region were found by PSORT; CPE1951.
    
  0.903
CPE2125
Conserved hypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.902
nadC
Nicotinate-nucleotide pyrophosphorylase; 279 aa, similar to pir:B70375 quinolinate phosphoribosyl transferase (EC 2.4.2.19) from Aquifex aeolicus (274 aa); 55.7% identity in 273 aa overlap; CPE0396; quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
     
 0.900
CPE1817
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.900
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.408
Your Current Organism:
Clostridium perfringens 13
NCBI taxonomy Id: 195102
Other names: C. perfringens str. 13, Clostridium perfringens str. 13
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